Show HN: GenoRxiv – Mapping scientific literature on the genome

3 points by Barneyhill a day ago

Ever get lost searching through genetic literature? I've built a new interface for bioRxiv+medRxiv to directly browse preprint findings on the genome!

To begin I downloaded 7TB's of bioRxiv+medRxiv preprints and extracted mentions of genetic variant ID's or positions. Documented in "How to download bioRxiv on a budget": http://sitlabs.org/writing/biorxiv.html

This project started after I was trawling through Google Scholar to review a gene when I realised I had missed relevant upstream findings which hadn't been linked to the gene. I wondered if there could be a better interface to explore genetic literature?

Next I provided the variant mentions and paper context to gpt-4o-mini and requested structured output summarising the scientific finding. Finally I mapped all variants to the latest genome build and plotted them on our custom genome browser.

This project was made by the new Scientific Interface & Tooling Lab (http://sitlabs.org) at Oxford. We will be releasing new interfaces and tools to improve scientific productivity with an initial focus on biology research.